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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c5ee8a93d727f34f88b2064086ac982342e43a8ab5716349bc7be02c8c1d011' 
  AND token = '+tcAGXQo7tWzJeyeN7VhNR8YWtXlJfN/hx73yVg0gQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}