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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '037deaea2bd40a2da42614531ce37d9ed221b075bdd07bfd7cdfa2d31335fefe' 
  AND token = 'vcULfsYAn6C42wYTqcPwCE+zRBzOLKthxt6L2kcB9zU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}