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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '411f58105d850a53b80b30184010f20136721418fe98e1481b7c2bcaae6a0c95' 
  AND token = 'tWyJ3Dv9F0nAS272e0JbiJFBGJT1tj0A6li6fHE8Da0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}