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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6f78208a486bf24cac0074cbb502e88192736a242397c1ac3173272e9445ee5' 
  AND token = 'MkmtXXYU2iLdps4Q4/z4gry/1YpY+M05c7CQw7hT+7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}