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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3972c4e318f06166cbfe611c8100469d0eee15486af4433e40582f1ab9a88785' 
  AND token = '+XykZ3eU2C1st+dMPGYE2YPV7ULK/CDe/ouEbCJ8x7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}