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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eba3b108e7a8727fa4ca1377c3687f4ee0f6c6e1348f357c53a326299b3ca411' 
  AND token = '/PWF1M3spRmQvt0/A55/7pysfKyaMoZJF9frOKKQqs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}