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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '859973d80f227d258dd9e324e287f2257ae9040d1c9195913b8d2550b274700c' 
  AND token = 'gzqZ+8eufjNocujwMUbWCfLf1W9gpKsmH1F1d+tnzEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}