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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '001a0d7989a7350bbccdbacca9a8540ff7a3287dc0cbf2002fdf7864a734c240' 
  AND token = '5FJ26Rrb/MQ43ZmB5bf06Ft/m7ULgkkTKoK3/oZdJrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}