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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55b686781b530d4f8168086d5bee372896d2d6e5a0fc2c9a841c964772ecf339' 
  AND token = 'ci/cW5Pwm7gujliTc4oOGEgvreyarw2DOunwppWOMfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}