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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '272002d98125a134113c2ecc70e3da7b7a459fabce117fec3bde2abd8a72ccbd' 
  AND token = 'BTU1STysuY6Gm0Gwj/j/6BbYA7eQthYsLPogL/oT1+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}