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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f1fbe38a6a2e3525390a311bdc05d944dabb5a3e1a1ecab822785939ab049be' 
  AND token = '0GVUFA0W0K62st7eDh5eM8hyv9CrnLHDTGNwkZ9KTeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}