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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e48518969537e63f4a6b89b33449bc5c8feb6fb5ba9f100b6ac15d9cf04f039' 
  AND token = '2mbcaBS8DTKWtsu6VgTb+QSax+T8StSAHWNCVAiO7yM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}