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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '387afb6bfc8da2a8f6927b02accb62ba76cded24c6a7b62712dcf2b9b8a3f9c1' 
  AND token = '16CYP/oaHuoCHsL1ekB5vAcrMKAscnOO5e5ZmYYv9sg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}