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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '234278e274183dec953a72f4fa5e0b9b7b260e6148a8ac6604d626854a0c752a' 
  AND token = 'IHeIptbx+/wTG1mBwPnkQMSEm4RDTEO0vDxxXZ+458w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}