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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6944def0e8ef4f687a157837ebbd9c3a5fcd9dcabc8bd71805bfafa9c218b1d' 
  AND token = '+Ctku5ZhdoB2NFDxy12+goVgmWeOFYRt0y5x4rJ61aQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}