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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8e925fd66463f2a52ad7fb2374d6e24c4c84482c17da0471f32e42b2ad62271' 
  AND token = 'cFvrqIUm/wzVvDqS8tsTE/8RQj2Pmu5WeriegDuzQeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}