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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1318d495f06006be14191bcb2dd486d7b319ac1720f14d3e2a11935861bb87e' 
  AND token = '20zQrTI5IOOlWD846rkwzF+PzDRGOEnCijBdmFk39RM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}