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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95a75d15cf632e707f323f689b34e6e49abc9e205b67b10b674dde4d7db5b848' 
  AND token = 'z5MXBsAOqhpI0/qyo30eoaGlPt8ZgJs1bWx7S6V00dI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}