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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd24db61f3e6970caf9f1091489f933f9a08261c5287db2cb3cd7c7732f20766d' 
  AND token = 'Y+f0UonEALkucrZl5F4QNQQzMIHnFGHtzjukfnph2q0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}