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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a066f68bb77832d4cdf41601f5ff11c1747d03b41b638016cf576f155bd46395' 
  AND token = 'nf149pLizFxzEZ/midb2N6RW1s76ehsofAMAU0z+Cvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}