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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8f80d818106c2780138c3e7c77e030c82bdf21fc11f05ff681a19337b247dc0' 
  AND token = 'aVUJQGGnFlxLfabFaKY8ZPHG2P7JZYrL5i6Dg8G9fUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}