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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38bdb08d66342eb56a3d49935dd4671a188e3a469d3ca9e81ae0e4911b137404' 
  AND token = 'T7O/I1sZZZkCW3QgOnEHoCvACy6ZiZh9qaFguSi8HBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}