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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2d8ee6305c216f7f02db3cd1b017de00a8768f832303261f63629b18569a38f' 
  AND token = '5Un5Us5ASkDi7+U+e5KCdyqGMpcbxyBWmYofOjm1Odw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}