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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '106096095c5a1f5379647e241730b64f8f7a5bbdcf4fed9842348804156c3449' 
  AND token = '5RnJCVAwwKmmxGmB1+OC6eDdnmYK0s1M3Q7Nw7o4Qqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}