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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3aa0aae83b143b9a9c4f00124f4455794787ac140030a29f3823dd8fe4db202' 
  AND token = 'mnFDhrwEAzdI9U0XYYzS163NYlM4L9f530YpeIWxYQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}