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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12dd182b89b1d2cef81b3a910de5392e009564e28dcfa9a8190b0d279878b9f0' 
  AND token = '6UwUkaZ6vCy/OHj02LESipnq997U30ZtBTTCc0F/rlA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}