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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c2c87de4efddcd85589676f2f9bf0072ca59bc496aa690ef8c0bd2dd768cf61' 
  AND token = 'wbbHK8FnZPG/F+M+tQxHghQJwNGPLNQPhmSsAc4dW2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}