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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aadeed5687840033040ce8c2d75540d431a37945ff6aafe1c3b04f9c557f56f7' 
  AND token = 'x1WU0I8YAyGeGIoTBppBY6Dq5g0zIUFEyrB2bu5KZ4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}