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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5acde69d2ef93a6120daf5293116033051ab847e1efd7b7d83d10a64643152da' 
  AND token = 'nu1BYu0nB2xZRQtXm2tsyoldCvOngxpaG6mqcdj7PZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}