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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0810b23cd02bae597958c77aeb6b46eb2d5f272bd94a80ec8e221a6f8d6975f1' 
  AND token = 'LMhjgTXoq81crVgwBzVSoJh+4ztC1jCTOoc9AdsUfeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}