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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '450fe6f14bd0cbf01c71579c28a1ca4b3a173b2a7c2ef0892ab7b8236a74b7cf' 
  AND token = 'Gkj8HlFqVrbQHZoYuXRTXx/u2NFhTqrep/H6o3YesPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}