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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c14c12bf79fbcd1866bb9b22fb503b70b856fdd5f6141dfeada95292e846a50e' 
  AND token = 'cH9ymxPp4nIVueQG8FbD+iYEr5sXgA3fBRoKGh34Tw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}