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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66fed4b9c6443cd22f9a22250c78e3fca46a5b1269e887530c3e66db9471bf1e' 
  AND token = 'IOFTEgcidMhq90kTVAjaz9zizqWJGh6VzRAbYNwgxw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}