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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e0d6dedf2cfe2708abe09d69241857bb5b1f38be90b08e05ece4608aec9e1aa' 
  AND token = '5+2UGYg5SMyuDYDva9y8jTwHhggFAU+lQzkqObR98P8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}