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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ad90ea2def465e5c47a0ac0eb238b1a8066e27437aac74ffbdc067d69c51227' 
  AND token = 'fsgj6oYt/y4VT8pFkjTaFyr1W6qZTE0jp1Z10uXXAGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}