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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '781c6d19082f053a60687ee7a723a5d41c669c7acdeb98f83d4ee935dd768a41' 
  AND token = 'IAnaw926QRxeVuzmexo79vLeyrqPIYXz1u1ScqSRRT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}