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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53bd7e936e52975ddc22c57855d7a2a6c4c7dee7d82490b2fb11dd3fb8aa6941' 
  AND token = '5eL/O0Thqq3TaQTS+c6jDh2VwrXwFESWTDhOQY8Ux0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}