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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '494a65c293649930a87b2d558ad70b54e7dea510dc9c69634fe692344a67c676' 
  AND token = 'EnWvuhe3R/JdNuMTq3C7y7sj79CUdUdt9sGNoV9uu9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}