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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '744e18dd22296c89d4734b5e4dc61da94693b4435ab1f25be3ac0dcafa438941' 
  AND token = '3AQlll/0ftKa+1Yga6z3NMs0s23pz2heRWY1HiR2xII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}