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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '423a60497f7fb95b153b6d7c87463045e30210d907353dcb50893de99a4a8d88' 
  AND token = 'FBI4W1umnCa0XC6dfjEuMIgO4dTVwISC17B6VY4fqBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}