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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea6747c6f223861eec9646f32daf8ebadc76b893e36f7fdb7bb63f94dd4fde4d' 
  AND token = 'gY6PjSMSD0E4lBw34ihf+fsYZTAuMTTyiqjz2d0apNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}