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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7da4dbd8fc4f00628e612e3581793eb7c3601da0231a4d4b9a36e5713db28e7c' 
  AND token = 'KePdEtGg62wnfhf/NKx+NQH0oqbUe/SzA1GdSA8/ygI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}