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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16c0cc1a1885fde22a4050d8fc08f347e3796e6c3268efcc89557632ddc40378' 
  AND token = 'h+nzKokQ76OwLRhd0y/kwPHAinBQ5oCY5QeB9pnWCLY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}