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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5787e814284fe34f6e1472682fcef63857945de35d7148c8a1ecf19ee5c59a19' 
  AND token = 'tHxhtxaVqIx8zsQefe4rzYf4FpeVCIC/FoTZ0Km3A0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}