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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5dd0aa58ee0118942647511cc7e72ef355034eb63f4fba7a549e77ebbddac68' 
  AND token = '2fDYmhDGgxWHL9EcW8rEE40ejo/Lau7ZCE7ixS3ALAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}