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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b7ee2134bd8f1b64432948764d5979705af6522f647093a1738038a99f1b833' 
  AND token = 'zQR1jy1Tw7YXrmcs11UdkIkK+3ucvoEeBTHNMzfvdzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}