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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '884308f177dcd9648a6dde3baa28df1e88c6bd7274918067160683f6e9a6244a' 
  AND token = 'H+AewDCrS8yjpIfg+KWgqc0+fUDcdFl58wEHLDw5P4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}