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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '330975041919704565b0161d38c77292ad520f9613cf60208327661e4b34d921' 
  AND token = 'ZWTKq06ssKdUvgQk52Zm+P0JBETRO38JYcm2MmF5WUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}