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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a63fff341ea77f59e992f24fefdae4a3ea91ba4183ecba5c7f659be0c1cf5923' 
  AND token = 'sTvzp+X42P2kaRFYHM9j6pONPDWRTZ/MPsNRMUw/Erg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}