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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f0eb22b77c31bba284ef03b0ddb3c60a60ca0f7b532f3083a6d9b47d6b022cc' 
  AND token = '+3fS/9AFTCXIO8yKp6OmozfgHpDCGIfDedGjLcYVfzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}